Connect with us

Local

Africa: World AIDS Day – This Is How We Can Fight the Second Biggest Killer of People with HIV

Published

on

38 Views

When I recently visited a hospital ward in Kinshasa, Democratic Republic of Congo, I left feeling deeply distraught. Over a dozen patients with HIV were admitted with cryptococcal meningitis – a fungal disease which is the second-leading cause of HIV- related death. Many were diagnosed late, which meant this disease, which causes excruciating headaches, fever and neck stiffness, had advanced so much it was increasingly difficult to treat them. To make things worse, the lifesaving treatment for cryptococcal meningitis was in limited supply, with stockouts common in this hospital.
In my more than decade-long experience as an HIV clinician and researcher, I’ve witnessed these scenarios repeatedly across many countries in Africa. Our hospitals not only often lack the resources and capacity to diagnose HIV opportunistic infections, but they are also forced to rely on toxic and inferior drugs when newer, more effective treatments are available. This is why over 70% of people with cryptococcal meningitis in low- and middle-income countries die while in high-income countries, where appropriate treatments are more widely used, mortality is around 20-30%
This is not just a healthcare issue – it’s a human rights crisis.
In 2023, AIDS-related illnesses claimed 390,000 lives in Africa, with cryptococcal meningitis responsible for nearly 130,000 of these deaths. These deaths persist because of the inequities that deny people in low- and middle-income countries (LMICs) access to treatment, violating their fundamental right to life.
For cryptococcal meningitis, the World Health Organization recommends a treatment regimen that includes liposomal amphotericin B (LAmB), flucytosine, and fluconazole. However, in Africa, two of these essential drugs – LAmB and flucytosine – are often unavailable, leaving many patients with a fluconazole monotherapy which is associated with a mortality of over 50%. According to the advanced HIV disease dashboard, only five of the 35 African countries it tracks have adopted LAmB as part of their treatment protocols and Mozambique is the only country to include it in its essential medicines list for cryptococcal meningitis.
In addition, low- and middle-income countries often pay more than high-income countries, despite bearing a far greater burden of HIV. For instance, Brazil pays $215 per vial of LAmB, while Japan and the UK pay $51 and $99, respectively. In 2021, only 28% of the
4.18 million vials sold globally went to LMICs. Such high costs discourage governments from prioritizing LAmB, forcing hospitals to continue using the amphotericin B deoxycholate formulation that has adverse side effects.
This isn’t just a healthcare crisis – it’s a crisis of equity.
When communities in poverty are denied access to essential medicines, it reflects a denial of their fundamental rights. As we mark World AIDS Day, this year’s theme,
“Take the Rights Path,” reminds us that access to healthcare is a fundamental human right enshrined in the Universal Declaration of Human Rights. Taking the Rights path means ensuring that medicines are:
Available – Treatments for cryptococcal meningitis are frequently unavailable at country-level in many African countries due to stockouts, supply and budgeting issues. In the case of LAmB, only two generic manufacturers exist today, and both are focusing on lucrative markets in high-income countries. While the Drugs for Neglected Diseases initiative (DNDi), in collaboration with Unitaid and the Clinton Health Access Initiative are working to expand availability by engaging new generic manufacturers to provide LAmB at affordable prices in Africa, more still needs to be done.
Accessible – We must urgently strengthen our healthcare systems to ensure that diagnostics and treatments reach even the most remote regions. Every person, whether in a village in Uganda or an urban slum in Nigeria, deserves access to the highest standard of care. African governments must act decisively by registering flucytosine and LAmB as essential medicines, ensuring they are available to those who need them most. Community leaders play a critical role in this fight; they must keep advocating for equitable healthcare and hold leaders accountable to extend medicine supply chains far beyond urban centers, reaching the millions whose lives depend on it.
Affordable – A practical way to make medicines more affordable is for countries and stakeholders to coordinate regionally through pooled procurement to promote competitive prices from manufacturers and suppliers. For example, The Global Fund’s Pooled Procurement Mechanism negotiates costs and delivery terms on behalf of countries. This strategy recently reduced the price of TLD, a first-line HIV treatment, to under $45 per person per year, enabling resource-limited governments to expand access to vital HIV services. This demonstrates how collective action can drive equity in healthcare.
Get the latest in African news delivered straight to your inbox
By submitting above, you agree to our privacy policy.
Almost finished…
We need to confirm your email address.
To complete the process, please follow the instructions in the email we just sent you.
There was a problem processing your submission. Please try again later.
Acceptable – Treatments must be available in formulations that are simple for communities and health workers to use. For instance, flucytosine currently requires it to be administered every six hours. Patients with cryptococcal meningitis are often unconscious when they arrive at the hospital, requiring healthcare staff to crush the tablets for administration via nasogastric tube -a method that has not been registered and that is very time-consuming. This is why my organization DNDi with our partners, including the pharmaceutical company Viatris, are developing a simpler version that requires only twice-daily dosage and can be administered via nasogastric tube.
Despite many efforts to improve the situation, there remains significant gaps including in the diagnosis of cryptococcal meningitis. Greater investment is needed to ensure diagnostics are also widely available, and to develop new, simplified treatments that are available at the primary healthcare level.
Access to diagnostics and treatments is not charity—it is justice. On this World AIDS Day, let us commit to taking the Rights path, ensuring no one is left behind in the fight against HIV.
A Tomato, Sex and HIV – The High Cost of Inequalities
Africa Records Decline in New HIV Infections, Aids-Related Deaths – WHO
AllAfrica publishes around 600 reports a day from more than 100 news organizations and over 500 other institutions and individuals, representing a diversity of positions on every topic. We publish news and views ranging from vigorous opponents of governments to government publications and spokespersons. Publishers named above each report are responsible for their own content, which AllAfrica does not have the legal right to edit or correct.
Articles and commentaries that identify allAfrica.com as the publisher are produced or commissioned by AllAfrica. To address comments or complaints, please Contact us.
AllAfrica is a voice of, by and about Africa – aggregating, producing and distributing 600 news and information items daily from over 100 African news organizations and our own reporters to an African and global public. We operate from Cape Town, Dakar, Abuja, Johannesburg, Nairobi and Washington DC.
Get the latest in African news delivered straight to your inbox
By submitting above, you agree to our privacy policy.
Almost finished…
We need to confirm your email address.
To complete the process, please follow the instructions in the email we just sent you.
There was a problem processing your submission. Please try again later.

source

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Local

Africa: Martin Luther King Jr's Legacy On Health Equity Through the Eyes of a Black African Doctor

Published

on

2 Views

Washington DC — Every year, January 20 is celebrated as Martin Luther King Jr. Day. He was a leader in the Civil Rights Movement who fought for equality and justice, especially for Black people, through peaceful protests and powerful speeches. The day is observed annually on the third Monday of January, close to his birthday on January 15. It is a time to remember his work, reflect on his message of fairness and nonviolence, and engage in acts of service to help others in our communities.
As a global health equity advocate, MLK Day holds special significance for me as a day to remember him as a health equity champion. He rightly identified health inequity as the worst form of social injustice. In his 1966 speech at the Second National Convention of the Medical Committee for Human Rights, MLK stated, “Of all the forms of inequality, injustice in health is the most shocking and inhuman”. I couldn’t agree more.
Globally, health inequities are numerous and mostly preventable. Neglected Tropical Diseases, maternal deaths, and malnutrition vividly reflect the global health injustices MLK foresaw
Growing up in Nigeria as a high school student in the 1980s, I was introduced to MLK through reading editions of Ebony magazine. I remember with nostalgia how I walked to roadside book sellers to buy old copies of the magazine.
These magazines introduced me to Black American social justice debates, including the works of MLK and Thurgood Marshall. It was an opportunity to connect spiritually with Africans in the diaspora – Black Americans – and their struggles. What struck me most as a child was MLK’s nonviolent demand for racial justice.
After high school, I went on to medical school in Nigeria to begin my training as a doctor. By the time I graduated in 1998, it was clear to me that patients’ rights must be respected in healthcare delivery. As health workers, we must prioritize preventive care while providing the care our patients need.
At the time, I did not know the right term for my convictions. Decades into my work in global health, I came to understand the term for my beliefs: health equity. In 2018, I delivered my first TEDx talk titled “Without Health We Have Nothing“. This is why MLK’s assertion that health injustice is the worst form of inequality resonates deeply with me. Healthcare – or its absence – is truly a matter of life and death.
Globally, health inequities are numerous and mostly preventable. Neglected Tropical Diseases, maternal deaths, and malnutrition vividly reflect the global health injustices MLK foresaw.
Neglected Tropical Diseases
Want to see a perfect example of diseases that disproportionately affect poor people? Look no further than Neglected Tropical Diseases (NTDs). These diseases affect 1.6 billion people globally, primarily in Africa and Asia. Many people do not realize some, like those mentioned in the Bible, still exist today.
A prime example is leprosy – a slow-growing bacterial infection that affects the skin, nerves, and sometimes the eyes and nose. Surprisingly, in 2024, the U.S. saw a significant rise in leprosy cases, particularly in the southeastern region, with central Florida identified as a hotspot.
Data reveals that approximately 34% of new cases reported between 2015 and 2020 were locally acquired. Without treatment, leprosy causes numb patches and potential deformities. Fortunately, leprosy is completely curable with antibiotics when caught early.
Other NTDs include river blindness, trachoma, and noma. Noma, in particular, is heartbreaking – it predominantly affects children between and six years who are malnourished, live in unhygienic conditions, or have weak immune systems.
Noma starts as a sore in the mouth but can destroy facial tissues, leaving severe deformities if untreated. Proper hygiene, nutrition, and healthcare can prevent noma, but it remains a reality in the poorest parts of the world.
Maternal Mortality
The United Nations Population Fund (UNFPA) captures the essence of safe motherhood with its statement: “No woman should die while giving life“. Tragically, for many women in low- and middle-income countries, and even wealthier nations, this isn’t the case.
In Nigeria alone, over 80,000 women die annually during pregnancy, childbirth, or shortly afterward. A professor once likened Nigeria’s high maternal mortality to filling a commercial jet with pregnant women every day and letting it crash – a haunting image. This huge injustice should not be allowed to continue.
In contrast, the United States of America has a higher maternal mortality rate compared to other wealthy countries, largely due to the disproportionately high maternal death rate among Black women. Black women are still 2 to 3 times more likely to die from pregnancy and childbirth than White women, regardless of their education level or socioeconomic status.
The solutions to stopping maternal deaths are not rocket science. Prenatal care must identify high-risk pregnancies, and women need access to proper nutrition to reduce the risks of postpartum hemorrhage, the leading cause of maternal deaths. With proper planning and preparation, including access to cesarean sections and emergency services, these deaths are preventable. Addressing these gaps would save countless lives.
Malnutrition
Malnutrition is a double-edged sword – it manifests as undernutrition (not enough nutrients) or overnutrition (eating too much). Both forms can be deadly, especially for children under five. Undernourished children fail to grow properly (wasting) and suffer impaired brain development, leading to stunting.
Get the latest in African news delivered straight to your inbox
By submitting above, you agree to our privacy policy.
Almost finished…
We need to confirm your email address.
To complete the process, please follow the instructions in the email we just sent you.
There was a problem processing your submission. Please try again later.
Globally, 22% of children are stunted, with 90% of cases occurring in Africa and Asia. On the other hand, overnutrition causes obesity, increasing the risk of non-communicable diseases like diabetes.
The solutions are simple: Support mothers to breastfeed exclusively for six months, educate communities on using affordable, local foods to prepare nutritious meals, and invest in school feeding programs. These steps would dramatically reduce malnutrition’s toll.
MLK’s vision for health justice shapes my global health equity journey. On MLK Day, let us reflect on global health injustices and commit to ending them. Identify one health issue you are passionate about and take meaningful action to address it.
MLK was right – health injustice is the worst form of inequality because without health we have nothing.
Happy MLK Day!
Dr. Ifeanyi M. Nsofor, a public-health physician, global health equity advocate and behavioral-science researcher, serves on the Global Fellows Advisory Board at the Atlantic Institute, Oxford, United Kingdom. You can follow him @Ifeanyi Nsofor, MD on LinkedIn
Follow @ekemma
Read the original article on IPS.
AllAfrica publishes around 400 reports a day from more than 110 news organizations and over 500 other institutions and individuals, representing a diversity of positions on every topic. We publish news and views ranging from vigorous opponents of governments to government publications and spokespersons. Publishers named above each report are responsible for their own content, which AllAfrica does not have the legal right to edit or correct.
Articles and commentaries that identify allAfrica.com as the publisher are produced or commissioned by AllAfrica. To address comments or complaints, please Contact us.
AllAfrica is a voice of, by and about Africa – aggregating, producing and distributing 400 news and information items daily from over 110 African news organizations and our own reporters to an African and global public. We operate from Cape Town, Dakar, Abuja, Johannesburg, Nairobi and Washington DC.
Get the latest in African news delivered straight to your inbox
By submitting above, you agree to our privacy policy.
Almost finished…
We need to confirm your email address.
To complete the process, please follow the instructions in the email we just sent you.
There was a problem processing your submission. Please try again later.

source

Continue Reading

Local

Africa: Holders Zamalek Lead Star-Studded TotalEnergies Confederation Cup Quarter-Finals

Published

on

5 Views

The TotalEnergies CAF Confederation Cup quarter-final line-up has been finalised with defending champions Zamalek leading a formidable array of clubs into the knock-out stages.
Eight teams from six nations will battle for continental glory when the quarter-finals commence on March 30, with the return legs scheduled for April 6.
Zamalek, who topped Group D with an impressive 14 points, are joined by fellow Egyptian side Al-Masry in the knockout stages.
The White Knights sealed their progress with a convincing 3-1 victory over Nigeria’s Enyimba on Sunday on the final matchday.
Tanzania’s Simba SC emerged as Group A winners, with Algeria’s CS Constantine securing second place.
Morocco’s Renaissance Berkane, previous winners of the competition, topped Group B ahead of South African debutants Stellenbosch.
USM Alger’s dominant Group C campaign saw them accumulate 14 points, while ASEC Mimosas of Cote d’Ivoire dramatically claimed the final quarter-final berth with a convincing victory on the last day.
The quarter-final draw will prevent teams from the same group meeting, meaning Egyptian rivals Zamalek and Al-Masry cannot face each other until at least the semi-finals.
Zamalek will face one of CS Constantine, Stellenbosch, or ASEC Mimosas, while Al-Masry could meet Simba, Berkane, or USM Alger.
The tournament’s knockout phase structure ensures home advantage will be crucial, with group winners hosting the decisive second legs. The semi-finals are scheduled for April 20 and 27, with the two-legged final set for May 17 and 25.
The presence of former champions Zamalek and Berkane, alongside ambitious clubs like Simba and USM Alger, suggests an intriguing battle lies ahead for Africa’s second-tier club crown.
Read the original article on CAF.
AllAfrica publishes around 400 reports a day from more than 110 news organizations and over 500 other institutions and individuals, representing a diversity of positions on every topic. We publish news and views ranging from vigorous opponents of governments to government publications and spokespersons. Publishers named above each report are responsible for their own content, which AllAfrica does not have the legal right to edit or correct.
Articles and commentaries that identify allAfrica.com as the publisher are produced or commissioned by AllAfrica. To address comments or complaints, please Contact us.
AllAfrica is a voice of, by and about Africa – aggregating, producing and distributing 400 news and information items daily from over 110 African news organizations and our own reporters to an African and global public. We operate from Cape Town, Dakar, Abuja, Johannesburg, Nairobi and Washington DC.
Get the latest in African news delivered straight to your inbox
By submitting above, you agree to our privacy policy.
Almost finished…
We need to confirm your email address.
To complete the process, please follow the instructions in the email we just sent you.
There was a problem processing your submission. Please try again later.

source

Continue Reading

Local

ConCourt dismisses bid to block Petauke by-election

Published

on

4 Views

By Hannock Kasama

The Constitutional Court has dismissed the application for a Conservatory Order to halt the PETAUKE Central Constituency by-election.

The application was recently filed by Governance Activist, ISAAC MWANZA and Zambia Civil Liberties Union.

However, the Constitutional Court has ruled that the application by Mr. MWANZA and the Zambia Civil Liberties Union has not outweighed public interest to hold the PETAUKE Central by-election.

Constitutional Court Judge, MATHEWS CHISUNKA has also ruled that Mr. MWANZA and the Zambia Civil Liberties Union have not demonstrated any prejudice they would suffer on account of the holding of the PETAUKE Central by-election.

Mr. MWANZA and the Zambia Civil Liberties Union had filed a petition in the Constitutional Court challenging the constitutionality of National Assembly Speaker NELLY MUTTI’s declaration of the PETAUKE Central seat vacant.

The post ConCourt dismisses bid to block Petauke by-election appeared first on ZNBC-Just for you.

source

Continue Reading

Trending

Copyright © 2024 an24.africa